Pineapple Express is hybrid marijuana strain. this strain has become a favorite in the hearts and minds of cannabis lovers. Pineapple Express is 27% THC and may make you feel buzzy, alert, and creative. The best time to smoke Pineapple Express is in the morning, afternoon, or early evening hours. Medical marijuana patients choose Pineapple Express to relieve symptoms associated with depression, pain, and fatigue. According to growers, this strain will flower into dense curly buds with dark green foliage and firey amber hairs.